Schisandrin

Product Name: Schisandrin
CAS No.: 7432-28-2
Chemical Name: Schisandrin
Synonyms: SCHISANDROL A;SCHIZANDRIN;SCHIZANDROL A;Schisandrol;SCHIZANDROL;12aR)-;schizandra;SCHISANDRIN;Schisadrol A;Schizandrin std.
CBNumber: CB3334838
Molecular Formula: C24H32O7
Formula Weight: 432.51
MOL File: 7432-28-2.mol

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Schisandrin Property

Melting point:: 128.5°C
Boiling point:: 466.17°C (rough estimate)
Density: 1.1480 (rough estimate)
refractive index: 1.5800 (estimate)
storage temp.: 2-8°C
solubility: DMSO: ≥13mg/mL
pka: 14.58±0.40(Predicted)
form: powder
color: white to beige
optical activity: [α]/D 75 to 95°, c = 1 in methanol
InChIKey: YEFOAORQXAOVJQ-UHFFFAOYSA-N
LogP: 3.153 (est)

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-50/53
Safety Statements: 60-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
HS Code: 29093090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0054
Product name: Schizandrin
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $82.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL89885
Product name: Schisandrol A
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $584
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1609895
Product name: Schisandrin
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15mg
Price: $344
Updated: 2024/03/01

Cayman Chemical

Product number: 27211
Product name: Schizandrin
Packaging: 10mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 27211
Product name: Schizandrin
Packaging: 250mg
Price: $887
Updated: 2024/03/01

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Schisandrin Chemical Properties,Usage,Production

Description

Schizandrin is a dibenzocyclooctadiene lignan and a major component of S. chinensis and has diverse biological activities. It induces cell cycle arrest at the G₀/G₁ phase and inhibits growth of T47D and MDA-MB-231 breast cancer cells when used at a concentration of 100 μM. Schizandrin (10 and 100 μM) prevents glutamate-induced cytotoxicity, inhibits production of nitric oxide (NO) and reactive oxygen species (ROS), and preserves the mitochondrial membrane potential in isolated rat cortical cells. It reduces apoptosis induced by cisplatin in HK-2 human kidney cells. In vivo, schizandrin (1 and 10 mg/kg, p.o.) reverses scopolamine-induced impairment of spatial memory and the passive avoidance response in rats. It enhances oxotremorine-induced tremors in mice. Schizandrin (10 mg/kg) reduces serum levels of IgE, IgG1, IL-4, and IFN-γ in an ovalbumin-sensitized mouse model of allergy.

Uses

Schizandrin may be used in oxidative stress-related cell signaling studies.

Application

Schizandrin is a natural compound that belongs to the group of schisandrins. Schizandrins are a class of compounds with biochemical properties and biological activities, such as anti-inflammatory, antioxidant, and anti-cancer effects. This compound has been shown to have pro-apoptotic properties in a model system. It has also demonstrated the ability to inhibit influenza A virus replication in vitro and protect mice against Listeria monocytogenes infection. It can be used as an inhibitor of gsh-px activity in myocardial infarcts.

Definition

ChEBI: Schizandrin is a tannin.

Biochem/physiol Actions

Schizandrin is a natural product with several biological properties involved with antioxidant and anti-inflammatory activities. It reduces the formation of ROS, inhibits the mitochondrial pathway of the apoptotic process and oxidative stress. Schizandrin has been reported to have hepatoprotective, antitumor, antiviral, and antiamnesic effects, and has neuroprotective activity against glutamate induced neurotoxicity.

Schisandrin Preparation Products And Raw materials

Raw materials

Preparation Products

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Schisandrin Suppliers

China 249 Germany 2 India 1 Japan 2 United Kingdom 8 United States 31 USA 1 Global 294

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8449
Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

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View Lastest Price from Schisandrin manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Schisandrin 7432-28-2
Price: US $0.00-0.00/MG
Min. Order: 10MG
Purity: 1-98% HPLC
Supply Ability: 100
Release date: 2022-11-30

Henan Tengmao Chemical Technology Co. LTD

Product: Schisandrin 7432-28-2
Price: US $110.00-90.00/kilogram
Min. Order: 1kilogram
Purity: 99%
Supply Ability: 10 tons/per week
Release date: 2023-12-19

Shanghai Standard Technology Co., Ltd.

Product: Schisandrin 7432-28-2
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-23

7432-28-2, SchisandrinRelated Search:

Dimethyl fumarate ETHANE Dimethyl sulfoxide Dimethyl phthalate S(-)-SCHISANDRIN,S(-) SCHISANDRIN B,SCHISANDRIN B,SCHISANDRIN, GAMMA-,GAMMA-SCHISANDRIN,SCHISANDRIN(SCHISANDROL A)(P) 4-Methoxybenzyl alcohol Schisandrin A N,N-Dimethylformamide Dimethyl carbonate Dimethyl sebacate Dimethyl ether Nortropine Gomisin A Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-1-ol, 5,6,7,8-tetrahydro-2, 3,13-trimethoxy-6,7-dimethyl-, stereoisomer 2-BUTENOIC ACID, 2-METHYL-, (5S,6S,7S,13AS)-5,6,7,13A-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YL ESTER, (2Z)- schisanhenol WUWEIZISU C Schisantherin A

SCHIZANDROL

Schisandrin,Schizandrin

chisandrin 5,6,7,8-Tetrahydro-6,7-dimethyl-1,2 3,10,11,12-hexamethoxydibenzo[a,c]cycloocten-6-ol

Schizandrin, >=98%

Schizandrin, 98%, from Schisandra chinensis (Turcz.) Baill.

Schisandrae Berry Extract

Schisandrol A 7432-28-2

SCHIZANDROL A

SCHIZANDRIN

SCHISANDRIN

SCHISANDROL A

WUWEIZI ALCOHOL A

SCHISANDRIN (SCHISANDROL A)

Schizandrin std.

Schisandrin（Schizandrol A）

Schisadrol A

dibenzo(a,c)cycloocten-6-ol,5,6,7,8-tetrahydro-6,7-dimethyl-1,23,10,11,12-hex

schizandra

5,6,7,8-Tetrahydro-6,7-dimethyl-1,2 3,10,11,12-hexamethoxydibenzo[a,c]cycloocten-6-ol

(+)-Schizandrin Schisandrin Schisandrine Wuweizi alcohol A Schizandrin

1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-,(6S,7S

12aR)-

Dibenzo[a,c]cycloocten-6-ol, 5,6,7,8-tetrahydro-

Schisandrol

5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-6-ol

Schisandrin (Schizandrol

Dibenzo[a,c]cycloocten-6-ol, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, (6S,7S,12aR)-

hot selling Schisandra Berries P.E

DeoxyschizandrinSchisandra chinensis extract

(6S,7S,12aR)-1,2,3,10,11,12-Hexamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulen-6-ol

Abametapir Impurity 29

Schisandrin methyl

7432-28-2

C24H32O7

Inhibitors

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Miscellaneous Natural Products

Natural Plant Extract

chemical reagent

pharmaceutical intermediate